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Offre de post-doc

 Chromatine et expression génique



 Publications de l'équipe (depuis 2003)



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Belton JM., Lajoie BR., Audibert A., Cantaloube C., Lassadi I., Goiffon I., Bau D., Marti-Renom M., Bystricky K. and Dekker J. “The recombination enhancer modulates the conformation of chromosome 3 in budding yeast.” Cell Reports, in press 2015
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Bayindir I., Babaeikelishomi R., Kocanova S., Sofia Sousa I., Lerch S., Hardt O., Wild S., Bosio A., Bystricky K., Herzig S, Vegiopoulos A.# “Transcriptional pathways in adipocyte progenitor activation for browning” Frontiers in Endocrinology, vol 6 2015
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Bystricky K.# “Chromosome dynamics and folding in eukaryotes: insights from live cell microscopy” FEBS Letters Special Issue 3D Genome Structure, in press pii: S0014-5793(15)00611-0. doi: 10.1016/j.febslet.2015.07.012. 2015 review
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Lassadi I.*, Kamgoué A*., Goiffon I., Tanguy-le-Gac N. and Bystricky K.# “Differential chromosome conformations as hallmarks of cellular identity revealed by mathematical polymer modeling. ” PLoS Computational Biology, DOI 10.1371/journal.pcbi.1004306, 2015
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de Cremoux P. #, Dalvai M., N’Doye O., Moutahir F., Rolland G., Chouchane-Mlik O., Assayag F., Lehmann-Che J.,Kraus-Berthier L., Nicolas A., Lockhart B.P., Marangoni E., de Thé H., Depil S., Bystricky K. and Decaudin D. “HDAC inhibition does not induce Estrogen Receptor in human triple negative breast cancer cell lines and Patient-Derived Xenografts. ” BCRT (Breast Cancer Research and Therapy) in press, 2014
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Queval R., Papin C., Dalvai M., Bystricky K. and Humbert O.# “Reptin and Pontin oligomerization and activity are modulated through histone H3 amino-terminal tail interaction.” JBC online 21 oct, 2014

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Lavigne A.-C. #, Castells M., Dalvai M., Mermet J., Kocanova S. and Bystricky K. «Increased macroH2A1.1 Expression Correlates with Poor Survival of Triple-Negative Breast Cancer Patients.” PLoS ONE, 9(6): e98930. doi:10.1371/journal.pone.0098930, 2014

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Gallardo F.*, Saad H.*, Dalvai M., Tanguy le Gac N., Lane D. and Bystricky K.# "Early steps of double strand break processing revealed by non-intrusive imaging of DNA loci in living cells." PLoS Genetics march 13, 2014

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Hajjoul H.*, Mathon J.*, Ranchon H., Goiffon I., Mocciconazzi J., Albert B., Carrivain P., Victor J.M., Gadal O., Bystricky K., Bancaud A..# "Chromosome dynamics in living yeast: quantitative determination of the physical parameters that govern chromatin movements" Genome Research, in press doi: 10.1101/gr.157008.113, 2013

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Dalvai M., Fleury L., Kocanova S., Bellucci L. and Bystricky K.# "Tip48/reptin required for promoter-enhancer crosstalk in transcription activation" PLoS Genetics,9(4): e1003387. doi:10.1371/journal.pgen.1003387 Article

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Bellucci L.*, Dalvai M.*, Kocanova S., Moutahir F. and Bystricky K.# « Activation of p21 by HDAC inhibitors requires H2A.Z » PLoS ONE, 8(1):e54102. doi:10.1371/ journal.pone.0054102.

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Dalvai M., Bellucci L., Fleury L., Lavigne AC., Moutahir F. and Bystricky K#. "H2AZ dependent intragenic looping regulates cyclin D1 expression". Oncogene, oct 29 doi 10.038 PMID:2318396, 2012 Article

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Bystricky K#, Gallardo F, Lane D, Dubarry N. « Visualisation de la position et de la dynamique de loci d'ADN dans les cellules vivantes en utilisant un nouveau groupe de petits opérateurs bactériens » PCT/EP2012/055258. WO/2012/127047 ; Patent

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Imen Lassadi and Kerstin Bystricky#, "Tracking of single and multiple genomic loci in living yeast cells" Methods Mol Biol, may 29, 2011

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Silvia Kocanova*, Mahta Mazaheri*, Stephanie Caze-Subra and Kerstin Bystricky# "Ligands specify estrogen receptor alpha nuclear localization and degradation." BMC Cell Biology 11:98, 2010. Article

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Medina P, Genovese S, Paillasse MR, Mazaheri M, Caze-Subra S, Bystricky K, Curini M, Silvente-Poirot S, Epifano F, Poirot M.
Auraptene is an inhibitor of cholesterol esterification and a modulator of estrogen receptors.
Mol Pharmacol. 2010 Nov;78(5):827-36 (Medline).

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Mathieu Dalvai, Kerstin Bystricky Cell Cycle and Anti-Estrogen Effects Synergize to Regulate Cell Proliferation and ER Target Gene Expression This is an open-access article distributed by PLoS ONE: Research Article, published 08 Jun 2010 10.1371/journal.pone.0011011 Article

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Silvia Kocanova*, Elizabeth Kerr*, Sehrish Rafique, Shelagh Boyle, Stephanie Caze-Subra, Wendy Bickmore# and Kerstin Bystricky# “Activation of estrogen responsive genes does not require nuclear co-localisation” PLoS Genetics Published online on April 22, 2010, doi:10.1371/journal.pgen.1000922 Article
commentaire, a la une du CNRS INSB

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Mathieu Dalvai and Kerstin Bystricky#, “The Role of Histone Modifications and Variants in Regulating Gene Expression in Breast Cancer” J Mam Gland Biology Neoplasia Vol. 15, Issue 1, P. 19, 2010. Article

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Hajjoul H, Kocanova S, Lassadi I, Bystricky K, Bancaud A. Lab-on-Chip for fast 3D particle tracking in living cells. Lab Chip. 2009 Nov 7; 9(21):3054-8. Article

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He S, Bystricky K, Leon S, François JM, Parrou JL. The Saccharomyces cerevisiae vacuolar acid trehalase is targeted at the cell surface for its physiological function. FEBS J. 2009 Oct;276(19):5432-46. Article

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Silvia Kocanova and Kerstin Bystricky# 2009 “Genome Duality” Genome Biology 10:308, 38 may 2009.

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Adriana Miele, Kerstin Bystricky#, Job Dekker#, 2009 “Yeast mating type loci form heterochromatic clusters through silencer protein-dependent long-range interactions” PLoS Genet. 2009 May;5(5) Medline

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Kerstin Bystricky, Haico van Attikum, Maria D. Montiel, Vincent Dion, Lutz Gehlen and Susan M.Gasser Regulation of nuclear positioning and dynamcis of the silent mating type loci by the yeast Ku70 complex, Mol Cell Biol 29(3), 2009 Medline

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Laurence Fleury, Marie Gerus*, Anne-Claire Lavigne*, Hélène Richard-Foy and Kerstin Bystricky Eliminating epigenetic barriers induces transient hormone-regulated gene expression in estrogen receptor negative breast cancer cells. Oncogene 27:4075-4085, 2008 Medline

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Baron S, Escande A, Alberola G, Bystricky K, Balaguer P, Richard-Foy H.
Estrogen receptor alpha and the AP1 complex cooperate during IGF-I- induced transcriptional activation of the pS2/TFF1 gene. J Biol Chem. 282(16):11732-41, 2007. Medline
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Lutz Gehlen, Angelo Rosa, Konstantin Klenin, Jörg Langowski, Susan M.Gasser and Kerstin Bystricky Spatially confined polymer chains: implications of chromatin fibre flexibility and peripheral anchoring on telomere–telomere interaction. J Phys: Condensed Matter 18: S245-252, 2006. (article)
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Bystricky, K., Laroche, T., van Houwe, G., Blaszczyk, M., and Gasser, S. M. Chromosome looping in yeast: telomere pairing and coordinated movement reflect anchoring efficiency and territorial organization. J Cell Biol 168, 375-387, 2005. Medline
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Bystricky, K., Heun, P., Gehlen, L., Langowski, J., and Gasser, S. M. Long-range compaction and flexibility of interphase chromatin in budding yeast analyzed by high-resolution imaging techniques. Proc Natl Acad Sci U S A 101, 16495-16500, 2004. Medline
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Dorigo, B.*, Schalch, T.*, Bystricky, K.*, and Richmond, T. J. (* co-premier avec étudiants encadrés) Chromatin fiber folding: requirement for the histone H4 N-terminal tail. J Mol Biol 327, 85-96, 2003. Medline




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